Manuela Profir received a M.Sc. degree in Mathematics in 2002, followed by a master in Geometry and Algebra in 2005 at the University of Iasi (Romania) and PhD in Differential Geometry at the University of Cagliari in 2009. From 2010 to 2012, she was beneficiary of a grant for young researchers, co-funded by EU and RAS, at CRS4, developing a research project about the mesh morphing techniques in CFD simulation and analysis codes, with a geometric and topological approach. Since 2012, at CRS4 she has been applying the moving mesh methods for the simulation and testing of the passive insertion of the control rods system in the case of a reactor emergency shutdown, in the framework of the FP7 MAXSIMA research project. Since 2016, in the framework of the H2020 SESAME project, she has been performing CFD simulations and modelling of pool type experiments and new generation reactor conceptual design. She regularly collaborates with the university and supervises undergraduate students for their professional training at CRS4.