The project builds on our research on brain visualization, and aims to create a software using our research methods usable in a laboratory environment. The software targets 3-D reconstruction and visualization of architectonic, neurophysiological and tract tracing data of primate cerebral cortex. Our emphasis is on providing interactive solutions to reconstruction and analysis problems by harnessing the power of new generation commodity graphics accelerators. We take as input data acquired in serially collected individual sections, in which the locations of outer and inner cortical boundaries, architectonic borders, electrode tracks, and labeled neurons are coded in X-Y coordinates. Linear and non-linear local transformations are interactively applied to sections for aligning them and minimizing distortions introduced by sectioning and histological procedures. Cortical surfaces are incrementally reconstructed during section manipulation using both direct triangulation and functional techniques. Using multipass rendering techniques, the system interactively generates realistic 3-D views that present in the same image the location of architectonic areas and the spatial location, density and cortical depth of the introduced data. The reconstructed brain can be resliced according to arbitrary planes and virtually dissected for showing sulcal banks without distortion. Application of this software to the analysis of data from our previous studies showed that this integrated system is a powerful tool for anatomo-functional correlation in highly convoluted brains and for comparing data from brains cut along different sectioning plans. The availability of low-cost, high performance graphics PC platforms makes this approach practical for everyday laboratory work.<\/p>\n","protected":false},"featured_media":12092,"template":"","meta":{"_acf_changed":false},"gruppo":[123],"class_list":["post-19773","projects","type-projects","status-publish","has-post-thumbnail","hentry","gruppo-data-intensive-computing-en"],"acf":{"title":"Software Tools for Primate Brain Reconstruction from Histological Sections","acronym":"BRAIN","project_uuid":"c7e19522-6418-11e4-917d-127e8ddc4b30","start_date":"01\/01\/2001","end_date":"01\/07\/2001","funder":"University of Parma","partners":"","team_members":[],"proj_website":"www.crs4.it\/vic\/","project_status":"Completed","project_coordinator":[{"ID":10233,"post_author":"4","post_date":"2025-06-30 17:23:13","post_date_gmt":"2025-06-30 15:23:13","post_content":"Enrico Gobbetti is the director of Visual and Data-intensive Computing (ViDiC) at the Center for Advanced Studies, Research, and Development in Sardinia (CRS4), Italy. He holds an Engineering degree (1989) and a Ph.D. degree (1993) in Computer Science from the Swiss Federal Institute of Technology in Lausanne (EPFL), as well as Full Professor Habilitations in Computer Science and Information Processing from the Italian Ministry of University and Research. Prior to joining CRS4, he held research and\/or teaching positions at the Swiss Federal Institute of Technology in Lausanne, the University of Maryland Baltimore County (UMBC), Baltimore MD, USA, and the Center of Excellence in Space Data and Information Sciences (NASA\/CESDIS), NASA Goddard Space Flight Center, Greenbelt MD, USA. At CRS4, Enrico develops and manages a research program in visual and data-intensive computing supported through institutional, industrial and government grants, including many national and international projects. His research spans many areas of visual and data-intensive computing and is widely published in major journals and conferences. The primary focus is the study and creation of innovative, intelligent, and scalable solutions for acquiring, creating, processing, distributing, exploring, and analyzing complex and\/or massive datasets derived from simulations or measurements of phenomena, objects, environments, or real-world processes. He regularly serves the scientific community through participation in editorial boards, program committees, working groups and steering boards, as well as through the organization and chairing of conferences. He is a Fellow of Eurographics.","post_title":"Enrico Gobbetti","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"enrico-gobbetti","to_ping":"","pinged":"","post_modified":"2026-04-05 20:11:27","post_modified_gmt":"2026-04-05 18:11:27","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/enrico-gobbetti\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":10141,"post_author":"4","post_date":"2025-06-30 17:22:03","post_date_gmt":"2025-06-30 15:22:03","post_content":"Fabio Bettio is an electronics engineer, software developer, and technologist specializing in visual computing and scientific visualization. He has strong expertise in GPU-accelerated and web-based rendering, with a solid background in C++, OpenGL\/WebGL, GLSL, and WebXR development. He is a contributor to OpenLIME, an open-source platform for interactive visualization and relightable model rendering in scientific and cultural heritage contexts. In addition to software development, he has extensive experience as a Linux system and HPC cluster administrator. He has developed tools for system and UPS monitoring, implemented automated backup solutions, and manages web infrastructures based on CMSs for research initiatives and international conferences such as Eurographics and EuroVis. His scientific contributions have been published in top-tier journals such as ACM Journal on Computing and Cultural Heritage (JOCCH), Computers & Graphics, IEEE Transactions on Visualization and Computer Graphics (TVCG), and Solar Energy. His work has also been presented at renowned international conferences, including Eurographics, EuroVis, ISMAR, and Digital Heritage.","post_title":"Fabio Bettio","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"fabio-bettio","to_ping":"","pinged":"","post_modified":"2026-04-05 20:10:10","post_modified_gmt":"2026-04-05 18:10:10","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/fabio-bettio\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"\n