{"id":19607,"date":"2025-07-03T18:21:12","date_gmt":"2025-07-03T16:21:12","guid":{"rendered":"https:\/\/www.crs4.it\/projects\/col-4\/"},"modified":"2026-04-02T12:35:02","modified_gmt":"2026-04-02T10:35:02","slug":"col-4","status":"publish","type":"projects","link":"https:\/\/www.crs4.it\/en\/projects\/col-4\/","title":{"rendered":"COL 4"},"content":{"rendered":"

Genetic modifiers predisposing to CKD in Alport and thin basement membrane nephropathy<\/p>\n","protected":false},"featured_media":0,"template":"","meta":{"_acf_changed":false},"gruppo":[],"class_list":["post-19607","projects","type-projects","status-publish","hentry"],"acf":{"title":"Genetic modifiers predisposing to CKD in Alport","acronym":"COL 4","project_uuid":"c1b1d9fa-07d6-11e6-a596-0030485a3849","start_date":"01\/03\/2016","end_date":"28\/02\/2019","funder":"European Renal Association \u2013 European Dialysis and Transplant Association ","partners":"","project_coordinator":[],"proj_website":"","project_status":"Completed","team_members":[{"ID":10128,"post_author":"4","post_date":"2025-06-30 17:21:58","post_date_gmt":"2025-06-30 15:21:58","post_content":"I am a Bioinformatician and Software Engineer with extensive experience in research.Since 2011, I have developed strong expertise in managing large-scale genomic and biological data from an NGS Core facility, integrating clinical and experimental data, tracking samples and data provenance, and ensuring the reproducibility and portability of analysis workflows.My skills range from programming to project planning, covering scripting, web services, and databases. I have a strong aptitude for problem-solving and teamwork.I earned my master's degree in Physics at the University of Cagliari in 2004. More recently, I obtained a Ph.D. with a thesis titled \"Analysis of somatic mutations in oncology liquid biopsies: the effectiveness of a data-driven approach.\"Currently, I am a Researcher in Bioinformatics at the Department of Biosciences of CRS4 (Center for Advanced Studies, Research and Development in Sardinia). My work focuses on the integration, traceability, interpretation, and intensive analysis of massive and heterogeneous biological data.As part of the Data Engineer & Computing team, I contributed to the development of CRS4's data-intensive computing infrastructure, which integrates computing and storage resources with the CRS4 Next Generation Sequencing Core. This infrastructure provides traceable automation and seamless management and analysis of sequencing data.","post_title":"Rossano Atzeni","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"rossano-atzeni","to_ping":"","pinged":"","post_modified":"2026-05-12 20:10:05","post_modified_gmt":"2026-05-12 18:10:05","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/rossano-atzeni\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":10206,"post_author":"4","post_date":"2025-06-30 17:22:41","post_date_gmt":"2025-06-30 15:22:41","post_content":"Roberto Cusano, responsible of NGS sequencing platform, works at the CRS4 since 2009 where he has specialized inNext Generation Sequencing. After graduating in Biotechnology at the University of Genoa, he worked in various public research centers and hospital institutions in Italy where he acquired vast experience (30 years) in biotechnology applied to research and diagnostics in the fields of molecular biology, rare diseases, oncology and transplantation genetics. Since his early working years he has specialized in techniques for manipulating and analyzing nucleic acids, in particular for genetic mapping and sequencing. The acquired skills are used both in the development of methods applied to diagnostics and research, and in providing scientific support and services to the scientific community. He is the author of 78 publications in international scientific journals subject to editorial control and with an H-index of 35","post_title":"Roberto Cusano","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"roberto-cusano","to_ping":"","pinged":"","post_modified":"2026-05-12 20:10:56","post_modified_gmt":"2026-05-12 18:10:56","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/roberto-cusano\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"\nCOL 4 - CRS4<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.crs4.it\/en\/projects\/col-4\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"COL 4 - CRS4\" \/>\n<meta property=\"og:description\" content=\"Genetic modifiers predisposing to CKD in Alport and thin basement membrane nephropathy\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.crs4.it\/en\/projects\/col-4\/\" \/>\n<meta property=\"og:site_name\" content=\"CRS4\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/pages\/CRS4\/153623948010688\" \/>\n<meta property=\"article:modified_time\" content=\"2026-04-02T10:35:02+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.crs4.it\\\/en\\\/projects\\\/col-4\\\/\",\"url\":\"https:\\\/\\\/www.crs4.it\\\/en\\\/projects\\\/col-4\\\/\",\"name\":\"COL 4 - CRS4\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.crs4.it\\\/en\\\/#website\"},\"datePublished\":\"2025-07-03T16:21:12+00:00\",\"dateModified\":\"2026-04-02T10:35:02+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.crs4.it\\\/en\\\/projects\\\/col-4\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.crs4.it\\\/en\\\/projects\\\/col-4\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.crs4.it\\\/en\\\/projects\\\/col-4\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.crs4.it\\\/en\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Projects\",\"item\":\"https:\\\/\\\/www.crs4.it\\\/en\\\/projects\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"COL 4\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.crs4.it\\\/en\\\/#website\",\"url\":\"https:\\\/\\\/www.crs4.it\\\/en\\\/\",\"name\":\"CRS4\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.crs4.it\\\/en\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.crs4.it\\\/en\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.crs4.it\\\/en\\\/#organization\",\"name\":\"CRS4\",\"url\":\"https:\\\/\\\/www.crs4.it\\\/en\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www.crs4.it\\\/en\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/www.crs4.it\\\/wp-content\\\/uploads\\\/CRS4.trentennale_3.png\",\"contentUrl\":\"https:\\\/\\\/www.crs4.it\\\/wp-content\\\/uploads\\\/CRS4.trentennale_3.png\",\"width\":1518,\"height\":577,\"caption\":\"CRS4\"},\"image\":{\"@id\":\"https:\\\/\\\/www.crs4.it\\\/en\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/pages\\\/CRS4\\\/153623948010688\",\"https:\\\/\\\/www.instagram.com\\\/crs4.it\\\/\",\"https:\\\/\\\/www.youtube.com\\\/CRS4video\",\"https:\\\/\\\/www.linkedin.com\\\/company\\\/crs4\",\"https:\\\/\\\/www.slideshare.net\\\/CRS4\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"COL 4 - CRS4","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.crs4.it\/en\/projects\/col-4\/","og_locale":"en_US","og_type":"article","og_title":"COL 4 - CRS4","og_description":"Genetic modifiers predisposing to CKD in Alport and thin basement membrane nephropathy","og_url":"https:\/\/www.crs4.it\/en\/projects\/col-4\/","og_site_name":"CRS4","article_publisher":"https:\/\/www.facebook.com\/pages\/CRS4\/153623948010688","article_modified_time":"2026-04-02T10:35:02+00:00","twitter_card":"summary_large_image","schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.crs4.it\/en\/projects\/col-4\/","url":"https:\/\/www.crs4.it\/en\/projects\/col-4\/","name":"COL 4 - CRS4","isPartOf":{"@id":"https:\/\/www.crs4.it\/en\/#website"},"datePublished":"2025-07-03T16:21:12+00:00","dateModified":"2026-04-02T10:35:02+00:00","breadcrumb":{"@id":"https:\/\/www.crs4.it\/en\/projects\/col-4\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.crs4.it\/en\/projects\/col-4\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.crs4.it\/en\/projects\/col-4\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.crs4.it\/en\/"},{"@type":"ListItem","position":2,"name":"Projects","item":"https:\/\/www.crs4.it\/en\/projects\/"},{"@type":"ListItem","position":3,"name":"COL 4"}]},{"@type":"WebSite","@id":"https:\/\/www.crs4.it\/en\/#website","url":"https:\/\/www.crs4.it\/en\/","name":"CRS4","description":"","publisher":{"@id":"https:\/\/www.crs4.it\/en\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.crs4.it\/en\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www.crs4.it\/en\/#organization","name":"CRS4","url":"https:\/\/www.crs4.it\/en\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.crs4.it\/en\/#\/schema\/logo\/image\/","url":"https:\/\/www.crs4.it\/wp-content\/uploads\/CRS4.trentennale_3.png","contentUrl":"https:\/\/www.crs4.it\/wp-content\/uploads\/CRS4.trentennale_3.png","width":1518,"height":577,"caption":"CRS4"},"image":{"@id":"https:\/\/www.crs4.it\/en\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/pages\/CRS4\/153623948010688","https:\/\/www.instagram.com\/crs4.it\/","https:\/\/www.youtube.com\/CRS4video","https:\/\/www.linkedin.com\/company\/crs4","https:\/\/www.slideshare.net\/CRS4"]}]}},"_links":{"self":[{"href":"https:\/\/www.crs4.it\/en\/wp-json\/wp\/v2\/projects\/19607","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.crs4.it\/en\/wp-json\/wp\/v2\/projects"}],"about":[{"href":"https:\/\/www.crs4.it\/en\/wp-json\/wp\/v2\/types\/projects"}],"version-history":[{"count":10,"href":"https:\/\/www.crs4.it\/en\/wp-json\/wp\/v2\/projects\/19607\/revisions"}],"predecessor-version":[{"id":602715,"href":"https:\/\/www.crs4.it\/en\/wp-json\/wp\/v2\/projects\/19607\/revisions\/602715"}],"wp:attachment":[{"href":"https:\/\/www.crs4.it\/en\/wp-json\/wp\/v2\/media?parent=19607"}],"wp:term":[{"taxonomy":"gruppo","embeddable":true,"href":"https:\/\/www.crs4.it\/en\/wp-json\/wp\/v2\/gruppo?post=19607"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}