{"id":18994,"date":"2025-07-03T18:20:19","date_gmt":"2025-07-03T16:20:19","guid":{"rendered":"https:\/\/www.crs4.it\/projects\/niasmic\/"},"modified":"2026-04-02T12:34:08","modified_gmt":"2026-04-02T10:34:08","slug":"niasmic","status":"publish","type":"projects","link":"https:\/\/www.crs4.it\/en\/projects\/niasmic\/","title":{"rendered":"NIASMIC"},"content":{"rendered":"<p>The project aims to develop a non-invasive protocol to analyze the genetic profile of ctDNA (circulating tumor DNA) extracted from liquid biopsy of haematological and oncological patients, through the application of next generation sequencing technologies (NGS) on a panel of genes.\u00a0<br \/>\nNIASMIC, promoted by the regional agency Sardegna Ricerche through the &#8220;Cluster top-down actions&#8221; program, is financed through the POR FESR of the Autonomous Region of Sardinia 2014-2020<\/p>\n","protected":false},"featured_media":0,"template":"","meta":{"_acf_changed":false},"gruppo":[],"class_list":["post-18994","projects","type-projects","status-publish","hentry"],"acf":{"title":"Non Invasive Analysis of Somatic Mutations In Cancer","acronym":"NIASMIC","project_uuid":"2a1cae69-3333-11e8-ae20-506b8da9258c","start_date":"14\/02\/2018","end_date":"18\/07\/2020","funder":"POR FESR SARDEGNA 2014 \u2013 2020 ASSE PRIORITARIO 1 \u201cRICERCA SCIENTIFICA, SVILUPPO TECNOLOGICO E INNOVAZIONE\u201d AZIONE 1.1.4","partners":"\n<table style=\"width:100%; border-collapse: collapse;\">\n  <tr>\n    <th style=\"border: 1px solid #ddd; padding: 8px; background-color: #f2f2f2;\">Nome<\/th>\n    <th style=\"border: 1px solid #ddd; padding: 8px; background-color: #f2f2f2;\">Nazione<\/th>\n    <th style=\"border: 1px solid #ddd; padding: 8px; background-color: #f2f2f2;\">Ruolo<\/th>\n  <\/tr>\n\n  <tr>\n    <td style=\"border: 1px solid #ddd; padding: 8px;\"><a href=\"http:\/\/www.aobrotzu.it\/\" target=\"_blank\">Azienda Ospedaliera &#x27;G.Brotzu&#x27;<\/a><\/td>\n    <td style=\"border: 1px solid #ddd; padding: 8px;\">Italy<\/td>\n    <td style=\"border: 1px solid #ddd; padding: 8px;\">Partner<\/td>\n  <\/tr>\n\n  <tr>\n    <td style=\"border: 1px solid #ddd; padding: 8px;\">Yenetics srl<\/td>\n    <td style=\"border: 1px solid #ddd; padding: 8px;\">Italy<\/td>\n    <td style=\"border: 1px solid #ddd; padding: 8px;\">Partner<\/td>\n  <\/tr>\n\n  <tr>\n    <td style=\"border: 1px solid #ddd; padding: 8px;\">NUREX srl<\/td>\n    <td style=\"border: 1px solid #ddd; padding: 8px;\">Italy<\/td>\n    <td style=\"border: 1px solid #ddd; padding: 8px;\">Partner<\/td>\n  <\/tr>\n\n  <tr>\n    <td style=\"border: 1px solid #ddd; padding: 8px;\">KITOS srl<\/td>\n    <td style=\"border: 1px solid #ddd; padding: 8px;\">Italy<\/td>\n    <td style=\"border: 1px solid #ddd; padding: 8px;\">Partner<\/td>\n  <\/tr>\n\n  <tr>\n    <td style=\"border: 1px solid #ddd; padding: 8px;\">BGT-Italia srl<\/td>\n    <td style=\"border: 1px solid #ddd; padding: 8px;\">Italy<\/td>\n    <td style=\"border: 1px solid #ddd; padding: 8px;\">Partner<\/td>\n  <\/tr>\n\n  <tr>\n    <td style=\"border: 1px solid #ddd; padding: 8px;\">Chrono-Benessere srl<\/td>\n    <td style=\"border: 1px solid #ddd; padding: 8px;\">Italy<\/td>\n    <td style=\"border: 1px solid #ddd; padding: 8px;\">Partner<\/td>\n  <\/tr>\n\n  <tr>\n    <td style=\"border: 1px solid #ddd; padding: 8px;\">Microtec srl<\/td>\n    <td style=\"border: 1px solid #ddd; padding: 8px;\">Italy<\/td>\n    <td style=\"border: 1px solid #ddd; padding: 8px;\">Partner<\/td>\n  <\/tr>\n\n  <tr>\n    <td style=\"border: 1px solid #ddd; padding: 8px;\">ARDEA srl<\/td>\n    <td style=\"border: 1px solid #ddd; padding: 8px;\">Italy<\/td>\n    <td style=\"border: 1px solid #ddd; padding: 8px;\">Partner<\/td>\n  <\/tr>\n<\/table>","project_coordinator":[],"proj_website":"http:\/\/niasmic.crs4.it\/","project_status":"Completed","team_members":[{"ID":10128,"post_author":"4","post_date":"2025-06-30 17:21:58","post_date_gmt":"2025-06-30 15:21:58","post_content":"I am a Bioinformatician and Software Engineer with extensive experience in research.Since 2011, I have developed strong expertise in managing large-scale genomic and biological data from an NGS Core facility, integrating clinical and experimental data, tracking samples and data provenance, and ensuring the reproducibility and portability of analysis workflows.My skills range from programming to project planning, covering scripting, web services, and databases. I have a strong aptitude for problem-solving and teamwork.I earned my master's degree in Physics at the University of Cagliari in 2004. More recently, I obtained a Ph.D. with a thesis titled \"Analysis of somatic mutations in oncology liquid biopsies: the effectiveness of a data-driven approach.\"Currently, I am a Researcher in Bioinformatics at the Department of Biosciences of CRS4 (Center for Advanced Studies, Research and Development in Sardinia). My work focuses on the integration, traceability, interpretation, and intensive analysis of massive and heterogeneous biological data.As part of the Data Engineer & Computing team, I contributed to the development of CRS4's data-intensive computing infrastructure, which integrates computing and storage resources with the CRS4 Next Generation Sequencing Core. This infrastructure provides traceable automation and seamless management and analysis of sequencing data.","post_title":"Rossano Atzeni","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"rossano-atzeni","to_ping":"","pinged":"","post_modified":"2026-04-05 18:10:05","post_modified_gmt":"2026-04-05 16:10:05","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/rossano-atzeni\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":10206,"post_author":"4","post_date":"2025-06-30 17:22:41","post_date_gmt":"2025-06-30 15:22:41","post_content":"Roberto Cusano, responsible of NGS sequencing platform, works at the CRS4 since 2009 where he has specialized inNext Generation Sequencing. After graduating in Biotechnology at the University of Genoa, he worked in various public research centers and hospital institutions in Italy where he acquired vast experience (30 years) in biotechnology applied to research and diagnostics in the fields of molecular biology, rare diseases, oncology and transplantation genetics. Since his early working years he has specialized in techniques for manipulating and analyzing nucleic acids, in particular for genetic mapping and sequencing. The acquired skills are used both in the development of methods applied to diagnostics and research, and in providing scientific support and services to the scientific community. He is the author of 78 publications in international scientific journals subject to editorial control and with an H-index of 35","post_title":"Roberto Cusano","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"roberto-cusano","to_ping":"","pinged":"","post_modified":"2026-04-05 18:10:50","post_modified_gmt":"2026-04-05 16:10:50","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/roberto-cusano\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>NIASMIC - CRS4<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.crs4.it\/en\/projects\/niasmic\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"NIASMIC - CRS4\" \/>\n<meta property=\"og:description\" content=\"The project aims to develop a non-invasive protocol to analyze the genetic profile of ctDNA (circulating tumor DNA) extracted from liquid biopsy of haematological and oncological patients, through the application of next generation sequencing technologies (NGS) on a panel of genes.\u00a0 NIASMIC, promoted by the regional agency Sardegna Ricerche through the &#8220;Cluster top-down actions&#8221; 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