The ARRDIA project, articulated in 3 different tranches from 2020 to 2025,\u00a0concerns the study of early tumour markers in workers and population of particular industrial areas of Sardinia, with particular reference to pleuropulmonary pathologies resulting from asbestos dust of industrial nature.
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\nThe project aims to develop innovative non-invasive methods to detect and monitor the tumours under study. In particular, the research aims at detecting MicroRNAs in the breath and plasma of ex-exposed people and comparison groups, in order to be able to intervene at an early stage and treat possible pathologies in a timely manner.
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\nFurther information and details can be found at the project Web site https:\/\/www.arrdia.it<\/a><\/p>\n","protected":false},"featured_media":11013,"template":"","meta":{"_acf_changed":false},"gruppo":[124],"class_list":["post-12706","projects","type-projects","status-publish","has-post-thumbnail","hentry","gruppo-high-performance-and-quantum-computing-biosciences-and-advanced-studies"],"acf":{"title":"Asbestos Related Respiratory Diseases in Industrial Area Ricerca di Base su marker tumorali precoci (Micro-RNAs) in lavoratori delle aree Industriali della Sardegna","acronym":"ARRDIA","project_uuid":"738de8f7-a24a-11ed-ab26-506b8d36975d","start_date":"31\/12\/2020","end_date":"30\/07\/2025","funder":"RAS Legge regionale 7 agosto 2007, n. 7 \u201cPromozione della Ricerca Scientifica e dell'Innovazione Tecnologica in Sardegna\u201d","partners":"\n
| Nome<\/th>\n | Nazione<\/th>\n | Ruolo<\/th>\n <\/tr>\n\n |
|---|---|---|
| Azienda di Rilievo Nazionale ed Alta Specializzazione G. Brotzu<\/a><\/td>\n | Italy<\/td>\n | Partner<\/td>\n <\/tr>\n\n |
| Universit\u00e0 degli Studi di Cagliari<\/a><\/td>\n | Italy<\/td>\n | Partner<\/td>\n <\/tr>\n\n |
| Associazione Italiana Esposti Amianto - AIEA,<\/a><\/td>\n | Italy<\/td>\n | Partner<\/td>\n <\/tr>\n\n |
| FONDAZIONE CENTRO SERVIZI ALLA PERSONA VILLAMAR<\/a><\/td>\n | Italy<\/td>\n | Partner<\/td>\n <\/tr>\n<\/table>","proj_website":"https:\/\/www.arrdia.it\/","project_status":"Execution","project_coordinator":[{"ID":10257,"post_author":"4","post_date":"2025-06-30 17:23:42","post_date_gmt":"2025-06-30 15:23:42","post_content":"Lidia Leoni is the High Performance and Quantum Computing, Biosciences and Advanced Studies director at the Center for Advanced Studies, Research, and Development in Sardinia (CRS4). She won a study grant from the European Economic Community and successfully attended a three-year course in information sciences and remote sensing. She is responsible for some of the most important CRS4 research and innovation projects. Her experience ranges from the use of large systems, to application development, to the management and maintenance of networks, systems and services for users. As a sector director, she is involved in several CRS4 projects and contributes to helping other researchers in their work. She is responsible for the biosciences and computational infrastructures of the center , for project services and manages the budget for the purchases of the computing center. Before joining CRS4, she worked at the Sardinia Research Consortium (CORISA), Regional Agrometeorological Service for Sardinia (SAR) and was a consultant for various institutions and companies.","post_title":"Lidia Leoni","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"lidia-leoni","to_ping":"","pinged":"","post_modified":"2026-04-05 18:11:41","post_modified_gmt":"2026-04-05 16:11:41","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/lidia-leoni\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"}],"team_members":[{"ID":10128,"post_author":"4","post_date":"2025-06-30 17:21:58","post_date_gmt":"2025-06-30 15:21:58","post_content":"I am a Bioinformatician and Software Engineer with extensive experience in research.Since 2011, I have developed strong expertise in managing large-scale genomic and biological data from an NGS Core facility, integrating clinical and experimental data, tracking samples and data provenance, and ensuring the reproducibility and portability of analysis workflows.My skills range from programming to project planning, covering scripting, web services, and databases. I have a strong aptitude for problem-solving and teamwork.I earned my master's degree in Physics at the University of Cagliari in 2004. More recently, I obtained a Ph.D. with a thesis titled \"Analysis of somatic mutations in oncology liquid biopsies: the effectiveness of a data-driven approach.\"Currently, I am a Researcher in Bioinformatics at the Department of Biosciences of CRS4 (Center for Advanced Studies, Research and Development in Sardinia). My work focuses on the integration, traceability, interpretation, and intensive analysis of massive and heterogeneous biological data.As part of the Data Engineer & Computing team, I contributed to the development of CRS4's data-intensive computing infrastructure, which integrates computing and storage resources with the CRS4 Next Generation Sequencing Core. This infrastructure provides traceable automation and seamless management and analysis of sequencing data.","post_title":"Rossano Atzeni","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"rossano-atzeni","to_ping":"","pinged":"","post_modified":"2026-04-05 18:10:05","post_modified_gmt":"2026-04-05 16:10:05","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/rossano-atzeni\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":10206,"post_author":"4","post_date":"2025-06-30 17:22:41","post_date_gmt":"2025-06-30 15:22:41","post_content":"Roberto Cusano, responsible of NGS sequencing platform, works at the CRS4 since 2009 where he has specialized inNext Generation Sequencing. After graduating in Biotechnology at the University of Genoa, he worked in various public research centers and hospital institutions in Italy where he acquired vast experience (30 years) in biotechnology applied to research and diagnostics in the fields of molecular biology, rare diseases, oncology and transplantation genetics. Since his early working years he has specialized in techniques for manipulating and analyzing nucleic acids, in particular for genetic mapping and sequencing. The acquired skills are used both in the development of methods applied to diagnostics and research, and in providing scientific support and services to the scientific community. He is the author of 78 publications in international scientific journals subject to editorial control and with an H-index of 35","post_title":"Roberto Cusano","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"roberto-cusano","to_ping":"","pinged":"","post_modified":"2026-04-05 18:10:50","post_modified_gmt":"2026-04-05 16:10:50","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/roberto-cusano\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":10295,"post_author":"4","post_date":"2025-06-30 17:24:30","post_date_gmt":"2025-06-30 15:24:30","post_content":"Jessica Milia is a technologist in Biosciences and Computational Infrastructures, Smart Project and Quantum Computing sector of CRS4, NGS Core program. She graduated in Biology in 2018 at the University of Cagliari with a thesis focused on the identification and characterization of HIV-1 reverse transcriptase enxyme inhibitors. She got her master's degree in Cellular and Molecular Biology in 2020 at the University of Cagliari. Her thesis was focused on the evaluation of immune response inhibition mediated by Zika Virus. From December 2020 to October 2021 she worked as Research Fellow in the Laboratory of Molecular Virology of Department of Life and Environmental Sciences (University of Cagliari). Her main activities were: - evaluation of Sars-CoV-2 viral proteins inhibition of innate immune system and identification of potential inhibitors; - identification of Sars-CoV-2 nsp13 enzyme inhibitors. From December 2021 to current she works in the NGS sequencing platform of CRS4. She is involved in nucleic acids libraries preparation, performing and monitoring of sequencing experiments for WGS, WES, RNA-Seq, target sequencing, 16s Metagenomics experiments, using Illumina instruments. She helps to evaluate quality and quantity of sequencing raw data and bioinformatic analysis results.","post_title":"Jessica Milia","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"jessica-milia","to_ping":"","pinged":"","post_modified":"2026-04-05 18:12:25","post_modified_gmt":"2026-04-05 16:12:25","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/jessica-milia\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"\n |