H2UB is intended to be a Life Science infrastructure aimed at fostering new drug development through a network of laboratories capable of providing basic, translational and preclinical research support using cutting-edge technologies.
\nGovernance of the Hub will be centralized and will provide support in regulatory, ethics and management, as well as organizational and dissemination. Expertise will be articulated in thematic platforms that will include:<\/p>\n
H2UB meets the need to manage and develop research infrastructure of high complexity. Its value is measured not only in the list of resources and services made available but also as a space where researchers can be stimulated to improve the way they do research by providing expertise, technology, and managerial support.
\n\u00a0
\nCRS4 will contribute to the:<\/p>\n
| Nome<\/th>\n | Nazione<\/th>\n | Ruolo<\/th>\n <\/tr>\n\n |
|---|---|---|
| IRCCS Ospedale Giannina Gaslini<\/a><\/td>\n | Italy<\/td>\n | Coordinator<\/td>\n <\/tr>\n\n |
| Universit\u00e0 di Genova<\/a><\/td>\n | Italy<\/td>\n | Partner<\/td>\n <\/tr>\n\n |
| Universit\u00e0 degli Studi di Cagliari<\/a><\/td>\n | Italy<\/td>\n | Partner<\/td>\n <\/tr>\n\n |
| Azienda di Rilievo Nazionale ed Alta Specializzazione G. Brotzu<\/a><\/td>\n | Italy<\/td>\n | Partner<\/td>\n <\/tr>\n\n |
| Azienda Ospedaliero - Universitaria di Cagliari<\/a><\/td>\n | Italy<\/td>\n | Partner<\/td>\n <\/tr>\n\n |
| Azienda Ospedaliera di Rilievo Nazionale e di Alta Specialit\u00e0 \u201cS. Giuseppe Moscati\u201d di Avellino<\/a><\/td>\n | Italy<\/td>\n | Partner<\/td>\n <\/tr>\n<\/table>","proj_website":"","project_image_header":false,"project_status":"Execution","project_coordinator":[{"ID":10233,"post_author":"4","post_date":"2025-06-30 17:23:13","post_date_gmt":"2025-06-30 15:23:13","post_content":"Enrico Gobbetti is the director of Visual and Data-intensive Computing (ViDiC) at the Center for Advanced Studies, Research, and Development in Sardinia (CRS4), Italy. He holds an Engineering degree (1989) and a Ph.D. degree (1993) in Computer Science from the Swiss Federal Institute of Technology in Lausanne (EPFL), as well as Full Professor Habilitations in Computer Science and Information Processing from the Italian Ministry of University and Research. Prior to joining CRS4, he held research and\/or teaching positions at the Swiss Federal Institute of Technology in Lausanne, the University of Maryland Baltimore County (UMBC), Baltimore MD, USA, and the Center of Excellence in Space Data and Information Sciences (NASA\/CESDIS), NASA Goddard Space Flight Center, Greenbelt MD, USA. At CRS4, Enrico develops and manages a research program in visual and data-intensive computing supported through institutional, industrial and government grants, including many national and international projects. His research spans many areas of visual and data-intensive computing and is widely published in major journals and conferences. The primary focus is the study and creation of innovative, intelligent, and scalable solutions for acquiring, creating, processing, distributing, exploring, and analyzing complex and\/or massive datasets derived from simulations or measurements of phenomena, objects, environments, or real-world processes. He regularly serves the scientific community through participation in editorial boards, program committees, working groups and steering boards, as well as through the organization and chairing of conferences. He is a Fellow of Eurographics.","post_title":"Enrico Gobbetti","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"enrico-gobbetti","to_ping":"","pinged":"","post_modified":"2026-04-05 18:11:20","post_modified_gmt":"2026-04-05 16:11:20","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/enrico-gobbetti\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":10055,"post_author":"4","post_date":"2025-06-30 17:25:40","post_date_gmt":"2025-06-30 15:25:40","post_content":"Massimo Pisu is a Senior Researcher and Permanent Project Leader (PPL) in Visual and Data-Intensive Computing (VIDIC) sector of CRS4. He earned with honors his Master Degree in Chemical Engineering from the University of Cagliari (1990) and his PhD from the University of Bologna (1994). Fields of expertise are focused on mathematical modelling and computing simulation of processes at various scale levels for application in chemistry, biology, biotechnology, environment, energy and advanced material sectors. He has been involved in several projects sponsored by the European Community, MIUR, Sardinian Regional Authorities, and by national and international industries. He serves as a reviewer for several international journals in the fields of chemical engineering, biotechnology, and bioengineering. He is coauthor of 3 patents and over 100 publications in international journals and conference proceedings.","post_title":"Massimo Pisu","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"massimo-pisu","to_ping":"","pinged":"","post_modified":"2026-04-05 18:13:25","post_modified_gmt":"2026-04-05 16:13:25","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/massimo-pisu\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"}],"team_members":[{"ID":10141,"post_author":"4","post_date":"2025-06-30 17:22:03","post_date_gmt":"2025-06-30 15:22:03","post_content":"Fabio Bettio is an electronics engineer, software developer, and technologist specializing in visual computing and scientific visualization. He has strong expertise in GPU-accelerated and web-based rendering, with a solid background in C++, OpenGL\/WebGL, GLSL, and WebXR development. He is a contributor to OpenLIME, an open-source platform for interactive visualization and relightable model rendering in scientific and cultural heritage contexts. In addition to software development, he has extensive experience as a Linux system and HPC cluster administrator. He has developed tools for system and UPS monitoring, implemented automated backup solutions, and manages web infrastructures based on CMSs for research initiatives and international conferences such as Eurographics and EuroVis. His scientific contributions have been published in top-tier journals such as ACM Journal on Computing and Cultural Heritage (JOCCH), Computers & Graphics, IEEE Transactions on Visualization and Computer Graphics (TVCG), and Solar Energy. His work has also been presented at renowned international conferences, including Eurographics, EuroVis, ISMAR, and Digital Heritage.","post_title":"Fabio Bettio","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"fabio-bettio","to_ping":"","pinged":"","post_modified":"2026-04-05 18:10:11","post_modified_gmt":"2026-04-05 16:10:11","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/fabio-bettio\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":10226,"post_author":"4","post_date":"2025-06-30 17:23:05","post_date_gmt":"2025-06-30 15:23:05","post_content":"Francesca coordinates the digital health research activities on the Visual and Data-intensive Computing Sector at CRS4 (prev. Research Programs Digital Health\/Healthcare Flows). Her research activity spans the opportunities and problems arising from the application of computer science to medicine, working on interoperability, traceability, telemedicine and modelling of data and processes in the clinical context. In her 20 years of research experience she has cultivated ongoing collaborations with public and private organisations, including research institutions, hospitals and industries operating in the health IT sector, with particular attention to the direct application of research results in clinical practice. She holds a Ph.D. in Innovation Sciences and Technologies from the University of Cagliari and a degree in Biomedical Engineering from the University of Genoa. Her present research interests are mainly focused on the modelling of biomedical data and processes, with a particular attention to interoperability and traceability, also in the perspective of the application of the FAIR Principles. In particular, she is currently working: on an integration profile about specimen tracking (SET profile), with the IHE PaLM Technical committee; on the modelling of genetic data through the openEHR formalism, with openEHR International; and a standard under development about provenance information in the biotechnology domain (Standard ISO 23494, ISO Technical Committee 276), with BBMRI-ERIC, the European research infrastructure for biobanking.","post_title":"Francesca Frexia","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"francesca-frexia","to_ping":"","pinged":"","post_modified":"2026-04-05 18:11:12","post_modified_gmt":"2026-04-05 16:11:12","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/francesca-frexia\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":10283,"post_author":"4","post_date":"2025-06-30 17:24:15","post_date_gmt":"2025-06-30 15:24:15","post_content":"Fabio Marton is a researcher in the Visual Computing (ViC) group at the Center for Advanced Studies, Research, and Development in Sardinia (CRS4). He holds a Laurea (M. Sc.) degree (1999) in Computer Engineering from the University of Padova. His current research interests include out-of-core data processing, compression multiresolution modeling and time-critical rendering. He has participated as a key developer in industrial and research projects that have led to the development of state-of-the-art tools for large scale model rendering. He has co-authored papers in major international refereed journals and conferences, including SIGGRAPH, Eurographics, and IEEE Visualization. He has been EGPGV (Eurographics Symposium on Parallel Graphics) symposium chair (Cagliari, 2012) and paper co-chair (Girona, 2013). He is IPC member for Web3D from 2011. He serves as reviewer for international computer graphics journals and conferences. Before joining CRS4, he worked on 3D scanning at LMTT Padova and Optonet Brescia.","post_title":"Fabio Marton","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"fabio-marton","to_ping":"","pinged":"","post_modified":"2026-04-05 18:12:07","post_modified_gmt":"2026-04-05 16:12:07","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/fabio-marton\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":10204,"post_author":"4","post_date":"2025-06-30 17:22:40","post_date_gmt":"2025-06-30 15:22:40","post_content":"Antonio Maria Cristini received a Laurea (M.Sc.) Degree in Physics from the University of Cagliari with a thesis on Molecular Dynamics on the first Beowulf cluster of Sardinia. Since 2000 he works at CRS4 in the industrial research project 3D CRS stack (3D Common Reflection Surface Stack). This application immediately became strategic for industrial processing and is often cited as an example of technological innovation. Antonio M. Cristini has recently become the promoter and coordinator of the use of advanced technologies in the field of high performance scientific computing.","post_title":"Antonio Maria Cristini","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"antonio-maria-cristini","to_ping":"","pinged":"","post_modified":"2026-04-05 18:10:48","post_modified_gmt":"2026-04-05 16:10:48","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/antonio-maria-cristini\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":10230,"post_author":"4","post_date":"2025-06-30 17:23:10","post_date_gmt":"2025-06-30 15:23:10","post_content":"Claudio Gallo is a senior researcher in the Imaging and Numerical Geophysics program of the Energy and Environment sector at the Centre for Advanced Studies, Research and Development in Sardinia (CRS4). He holds a Laurea (M.Sc.) Degree in Chemical Engineering (1991) from the University of Padova (Italy) and a Ph.D. in Civil Engineering and Earth Sciences (2003) from the Technical University of Delft (Holland). His research focused for 12 years (1993-2004) on computational hydrology and then on numerical methods for processing acoustic seismic data (2004-today). He has published in major journals and conferences and authored book chapters. He is a reviewer for several international journals (Transport in Porous Media, Hydrogeology Journal, Vadose Zone Journal). He has taught in advanced courses on groundwater modeling and geostatistics at various universities and institutions. Since 10 years he works for hobby on financial modeling algorithms and on implementation of trading systems. On this topic he has published a book (2007) and a chapter in another book (published in July 2010 by Springer). He practices athletics (200m and 400m track-field runner) and he plays both acoustic and classic guitars.","post_title":"Claudio Gallo","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"claudio-gallo","to_ping":"","pinged":"","post_modified":"2026-04-05 18:11:17","post_modified_gmt":"2026-04-05 16:11:17","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/claudio-gallo\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":9982,"post_author":"4","post_date":"2025-06-30 17:26:25","post_date_gmt":"2025-06-30 15:26:25","post_content":"Electronic Engineer, Ph.D. in Mathematics.Research experience High resolution imaging, elastic reverse time migration, methods for ultrasound analysis, inversion of gravimetric data. Wave equation processes and modelling, numerical methods for computational geophysics, signal processing and data analysis, elastic forward problem and full waveform inversion, acoustic seismic imaging in depth and time, software development and testing of large scale industrial HPC applications. Data-driven optimization strategies in presence of relative minima, innovative extrapolation operators for downward continuation in the wavenumber domain, high resolution Radon transform for multiple attenuation in the image domain, polarization analysis of downhole seismic data, coherent noise reduction by Wavelet transform. Ill-posed inverse problems, regularization techniques for ill-conditioned algebraic problems, least squares solution of large Toeplitz linear systems, structured matrix algorithms for inverse scattering on the line, spatial resolution enhancement of microwave scanning radiometer data. Scientific supervision, team coordination, recruiting, project design and planning, resource allocation, procurement and management of industrial contracts. Publications restricted by NDA constraints.","post_title":"Daniela Theis","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"daniela-theis","to_ping":"","pinged":"","post_modified":"2026-04-05 18:14:01","post_modified_gmt":"2026-04-05 16:14:01","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/daniela-theis\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":10257,"post_author":"4","post_date":"2025-06-30 17:23:42","post_date_gmt":"2025-06-30 15:23:42","post_content":"Lidia Leoni is the High Performance and Quantum Computing, Biosciences and Advanced Studies director at the Center for Advanced Studies, Research, and Development in Sardinia (CRS4). She won a study grant from the European Economic Community and successfully attended a three-year course in information sciences and remote sensing. She is responsible for some of the most important CRS4 research and innovation projects. Her experience ranges from the use of large systems, to application development, to the management and maintenance of networks, systems and services for users. As a sector director, she is involved in several CRS4 projects and contributes to helping other researchers in their work. She is responsible for the biosciences and computational infrastructures of the center , for project services and manages the budget for the purchases of the computing center. Before joining CRS4, she worked at the Sardinia Research Consortium (CORISA), Regional Agrometeorological Service for Sardinia (SAR) and was a consultant for various institutions and companies.","post_title":"Lidia Leoni","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"lidia-leoni","to_ping":"","pinged":"","post_modified":"2026-04-05 18:11:41","post_modified_gmt":"2026-04-05 16:11:41","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/lidia-leoni\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":9921,"post_author":"4","post_date":"2025-06-30 17:26:41","post_date_gmt":"2025-06-30 15:26:41","post_content":"Matteo Vocale holds an Engineering degree from the University of Bologna (Italy). Since 2003 he is a network and security administrator both for CRS4 and the Campus network infrastructure. Currently he is the network and security team leader within the CRS4 ISCR group. Moreover, he is involved in research projects (CyberSAR, GRIDA3, etc), implementing data-grid tools to manage and share resources and data geographically distributed in several administrative domains. Matteo has always been interested in innovative technologies, such as C\/DWDM, Layer 1 MEMS-based optical switch, the first 10G ethernet server adapter from Intel, MPLS, IPv6 and the last technology named FCoE, capable of carrying Fibre Channel traffic over 10G Ethernet links","post_title":"Matteo Vocale","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"matteo-vocale","to_ping":"","pinged":"","post_modified":"2026-04-05 18:14:12","post_modified_gmt":"2026-04-05 16:14:12","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/matteo-vocale\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":10199,"post_author":"4","post_date":"2025-06-30 17:22:35","post_date_gmt":"2025-06-30 15:22:35","post_content":"Antonio is a Technologist, with a long experience. He works in HPCN group, is responsible for administration of Unix \/ Linux and Windows systems, the e-mail management and storage system in the center. Together with other colleagues is working at the implementation and maintenance of high-performance file system to support the needs of the computing cluster.","post_title":"Antonio Concas","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"antonio-concas","to_ping":"","pinged":"","post_modified":"2026-04-05 18:10:41","post_modified_gmt":"2026-04-05 16:10:41","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/antonio-concas\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":10112,"post_author":"4","post_date":"2025-06-30 17:25:04","post_date_gmt":"2025-06-30 15:25:04","post_content":"Enrico graduated in Physics from the University of Pisa in 1990, with a thesis on hardware and software for the SLD detector at Stanford. He then spent three years developing 2D-3D lattice Gross-Neveu models at the Theoretical Group in the Department of Physics, University of Pisa. In 1994, he joined CRS4, where he began working on parallel algorithms for supercomputing\/HPC and on models for the propagation and inversion of acoustic, elastic, and electromagnetic waves, with applications in geophysics (Agip, Unica) and biomedicine (ultrasound, Esaote).In 2005, he started collaborating with CRS4's Systems Biology group, developing tools for the analysis of complex gene\/protein interaction networks and methodologies for reverse engineering microarray data. In 2008, he worked on data mining tools for constructing force fields for molecular dynamics, applying an original optimization approach adaptable to multiscale biological problems. This research led to a joint international patent on the prediction of molecular properties. In 2009, he contributed to developing an algorithm for haplotyping human mitochondrial DNA, deposited on SourceForge. In 2010, he briefly collaborated with the CRS4 AGCT group on parallelizing genotyping and data selection algorithms.Since 2005, his main interests have centered on computational chemistry and biophysics. In collaboration with the Binaghi Hospital in Cagliari, he developed molecular models of the immune system related to the onset of multiple sclerosis, and with the University of Cagliari, he worked on modeling inflammatory processes and potential drugs for Alzheimer's treatment, as well as on painkillers, medications, and antivirals. More recently, he has focused on designing nanomaterials with biomedical and agri-food applications.Occasionally, he writes books, develops educational e-learning projects in physics, delivers seminars on medical devices, physics, computational modeling, and mathematics, and oversees and reviews ICT research and development projects in Italy and Europe. He has tutored two graduates, mentored a Ph.D. candidate, and served as a co-supervisor for both a master's and a doctoral thesis. Enrico holds a Master's degree in Bioinformatics and a Ph.D. in Biomedical Engineering.General bibliographical metrics and SCOPUS covered publicationsGeneral bibliographical metrics and ORCID covered publicationsHigh Energy Physics metricsHigh Energy Physics publications","post_title":"Enrico Pieroni","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"enrico-pieroni","to_ping":"","pinged":"","post_modified":"2026-04-05 18:12:56","post_modified_gmt":"2026-04-05 16:12:56","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/enrico-pieroni\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":9971,"post_author":"4","post_date":"2025-06-30 17:26:32","post_date_gmt":"2025-06-30 15:26:32","post_content":"Maria graduated in Physics in 1991 from the University of Bologna with a thesis in Cosmology on the structure and large-scale motions of the Universe. In 1992 she started working in the parallel computing group of the newly founded CRS4 on the parallelisation of molecular dynamics codes. In April 1994, she was awarded a Marie-Curie FP6 fellowship at the CNRS Laboratoire des Physique des Milieux Ionise (LPMI), Ecole Polytechnique, Palaiseu, France. In 1998, she obtained her PhD in Plasma Physics at the Ecole Doctorale de Troisime Cycle de l'Ecole Polytechnique with a thesis on the theoretical and computational analysis of the motion of charged particles in electromagnetic fields. Since May 1999, she has been an expert researcher in the Fuel Cells area of CRS4, working on molecular dynamics simulations of proton-conducting membranes and the development of a finite volume code for electrochemical systems.In May 2006, she moved to the Bioinformatics group at CRS4, where she worked on protein structure and dynamics. In the same year, she obtained a master's degree in Bionformatics with a thesis on large-scale protein-protein docking. Since the beginning of 2010, she has been a member of the AGCT group at CRS4, where she worked on data analysis for case-control studies on genetic diseases. She currently works as a Senior Researcher in the Simulation&Modelling group at CRS4. Maria is interested in studying the structure and dynamics of proteins and new materials for real cases and through the development of new methodologies and force fields.","post_title":"Maria Valentini","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"maria-valentini","to_ping":"","pinged":"","post_modified":"2026-04-05 18:14:06","post_modified_gmt":"2026-04-05 16:14:06","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/maria-valentini\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":10066,"post_author":"4","post_date":"2025-06-30 17:25:33","post_date_gmt":"2025-06-30 15:25:33","post_content":"Luca Pireddu earned his degree in Computing Science in 2003 from Laurentian University in Sudbury, Canada. Here he also started his research work joining MIRARCO in 2002, where he completed his undergraduate thesis on computational methods to optimize underground mine plans. He later pursued graduate studies at the University of Alberta, Canada, receiving his M.Sc. in Computing Science in 2006 with a thesis on predicting biological pathways by proteome analysis - a project that he continued as a researcher at U. of A. after his studies. After a stint in the private sector, Luca joined CRS4, where he currently works with the Visual and Data-Intensive Computing group. He has coordinated CRS4's participation in several EU, national and regional research projects in the area of novel development and application of data processing, analysis and management techniques to concrete problems in several fields of interest - particularly, bioinformatics, biomedical research and urban computing. He is particularly interested in techniques for facilitating scalability of complex computational scientific workflows, secure and scalable methods to leverage sensitive data collections, and data and workflow re-use through the application of FAIR principles. He represents CRS4 at the Italian nodes of the BBMRI-ERIC and ELIXIR EU Research Infrastructures and at the Data, AI and Robotics (DAIRO) Association (ex BDVA).","post_title":"Luca Pireddu","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"luca-pireddu","to_ping":"","pinged":"","post_modified":"2026-04-05 18:13:19","post_modified_gmt":"2026-04-05 16:13:19","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/luca-pireddu\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":10306,"post_author":"4","post_date":"2025-06-30 17:24:44","post_date_gmt":"2025-06-30 15:24:44","post_content":"Network and System Engineer, Marco is currently working in the High Performance Computing group. He also develops research and computing oriented solutions that meets the newest technological innovations. He is an experienced Windows and Unix-like admin,High Availability services manager and network administrator. Marco holds a degree in Ingegneria Elettronica from Universit\u00e0 degli Studi di Cagliari.","post_title":"Marco Moro","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"marco-moro","to_ping":"","pinged":"","post_modified":"2026-04-05 18:12:39","post_modified_gmt":"2026-04-05 16:12:39","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/marco-moro\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":10164,"post_author":"4","post_date":"2025-06-30 17:22:14","post_date_gmt":"2025-06-30 15:22:14","post_content":"Giovanni Busonera received his M.Sc. in Electronic Engineering from the University of Cagliari in 2004 and the Ph.D. in Electronic Engineering and Computer Science from the same University in 2008. Since 2008 he works at CRS4 as a researcher. His research interests concerned mainly virtualization, distributed programming and hardware acceleration for parallel computing by using GPGPU and FPGA devices. Before joining CRS4, he worked in the Microsoft Research Embedded Group in Redmond developing eBug, a software debugging support for the dynamically reconfigurable processor eMIPS. He also worked on the development of a haplotyping algorithm to perform multi-marker genome wide association study (GWAS). Currently his work deals with signal processing and data analysis for biomedical applications and statistical methods for network traffic modeling.","post_title":"Giovanni Busonera","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"giovanni-busonera","to_ping":"","pinged":"","post_modified":"2026-04-05 18:10:21","post_modified_gmt":"2026-04-05 16:10:21","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/giovanni-busonera\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":10191,"post_author":"4","post_date":"2025-06-30 17:22:30","post_date_gmt":"2025-06-30 15:22:30","post_content":"Degree in Physics at Universit\u00e0 di Cagliari in 1999 with a dissertation on the chaotic behavior of spin glasses (with E. Marinari and later M. Mezard.) Ph.D in Physics obtained at Universit\u00e0 di Cagliari with a dissertation on the creation and the mobility of defects in crystalline semiconductors (with Luciano Colombo and Art Voter.) Post-doc researcher at Physics Department (Universit\u00e0 di Cagliari) (2003-2005), Materials Science at Universit\u00e0 di Milano Bicocca (with Leo Miglio) (2005-2007), CNRS Laboratoire de Mecanique de Lille and CEA Saclay (J.P. Laval, B. Dubrulle) (2007-2008). Since 2008 at CRS4, working on different projects related to concentrated solar power, crystalline structure of ice and, recently, network congestion analysis, feature extraction from biological signals and applications of network theory to social sciences. The research activity is characterized by the use and development of advanced numerical techniques such as Montecarlo methods, multi-objective optimization and statistical mechanics tools.","post_title":"Marco Cogoni","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"marco-cogoni","to_ping":"","pinged":"","post_modified":"2026-04-05 18:10:35","post_modified_gmt":"2026-04-05 16:10:35","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/marco-cogoni\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":10096,"post_author":"4","post_date":"2025-06-30 17:25:14","post_date_gmt":"2025-06-30 15:25:14","post_content":"Andrea Pinna is a research scientist in the Digital Technologies sector at CRS4. He holds a Ph.D. in Electronic and Computer Engineering and a M.Sc. degree in Electronic Engineering, both from the University of Cagliari. He has expertise in multidisciplinary research areas, particularly in the development of scientific software, such as decision support systems for precision agriculture and for estimating photovoltaic production in urban areas, modeling of biochemical and biological systems, implementation of identification algorithms, design of simulation software, and development and management of high-performance computing workflows. This experience has been gained through collaboration with research groups affiliated with various sectors (Bioinformatics and HPC for Energy and Environment at CRS4, University of Cagliari, Cagliari Astronomical Observatory), and thanks to study and work experiences at international institutions such as Delft University of Technology (Netherlands) and the Materials and Microsystems group at Siemens (Germany).","post_title":"Andrea Pinna","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"andrea-pinna","to_ping":"","pinged":"","post_modified":"2026-04-05 18:13:03","post_modified_gmt":"2026-04-05 16:13:03","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/andrea-pinna\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":10259,"post_author":"4","post_date":"2025-06-30 17:23:44","post_date_gmt":"2025-06-30 15:23:44","post_content":"After graduating in Computer Science at the University of Cagliari in 2006, he joined the Digital Health group of CRS4, directing his research activity to the application of ICT in the clinical and biomedical fields, mainly in the areas of telemedicine, interoperability between clinical systems and creation of systems for the treatment of large amounts of biomedical data. His current research interests are focused on the management of complex and heterogeneous clinical data with open standard formats (such as openEHR and HL7-FHIR) and on Digital Pathology. In this area in particular, he has designed and implemented the CRS4 Digital Pathology platform to support diagnosis from digitized slides, collaborating with leading clinical institutions such as the Karolinska Institutet in Stockholm and the COREP consortium. The platform allows to handle, view and annotate scanned images, and it is the core of several use cases in the context of international research projects, focused on remote training (CyTest), clinical trials (ProMort Study) and Artificial Intelligence models' development from annotated images (DeepHealth).","post_title":"Luca Lianas","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"luca-lianas","to_ping":"","pinged":"","post_modified":"2026-04-05 18:11:43","post_modified_gmt":"2026-04-05 16:11:43","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/luca-lianas\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":10128,"post_author":"4","post_date":"2025-06-30 17:21:58","post_date_gmt":"2025-06-30 15:21:58","post_content":"I am a Bioinformatician and Software Engineer with extensive experience in research.Since 2011, I have developed strong expertise in managing large-scale genomic and biological data from an NGS Core facility, integrating clinical and experimental data, tracking samples and data provenance, and ensuring the reproducibility and portability of analysis workflows.My skills range from programming to project planning, covering scripting, web services, and databases. I have a strong aptitude for problem-solving and teamwork.I earned my master's degree in Physics at the University of Cagliari in 2004. More recently, I obtained a Ph.D. with a thesis titled \"Analysis of somatic mutations in oncology liquid biopsies: the effectiveness of a data-driven approach.\"Currently, I am a Researcher in Bioinformatics at the Department of Biosciences of CRS4 (Center for Advanced Studies, Research and Development in Sardinia). My work focuses on the integration, traceability, interpretation, and intensive analysis of massive and heterogeneous biological data.As part of the Data Engineer & Computing team, I contributed to the development of CRS4's data-intensive computing infrastructure, which integrates computing and storage resources with the CRS4 Next Generation Sequencing Core. This infrastructure provides traceable automation and seamless management and analysis of sequencing data.","post_title":"Rossano Atzeni","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"rossano-atzeni","to_ping":"","pinged":"","post_modified":"2026-04-05 18:10:05","post_modified_gmt":"2026-04-05 16:10:05","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/rossano-atzeni\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":10206,"post_author":"4","post_date":"2025-06-30 17:22:41","post_date_gmt":"2025-06-30 15:22:41","post_content":"Roberto Cusano, responsible of NGS sequencing platform, works at the CRS4 since 2009 where he has specialized inNext Generation Sequencing. After graduating in Biotechnology at the University of Genoa, he worked in various public research centers and hospital institutions in Italy where he acquired vast experience (30 years) in biotechnology applied to research and diagnostics in the fields of molecular biology, rare diseases, oncology and transplantation genetics. Since his early working years he has specialized in techniques for manipulating and analyzing nucleic acids, in particular for genetic mapping and sequencing. The acquired skills are used both in the development of methods applied to diagnostics and research, and in providing scientific support and services to the scientific community. He is the author of 78 publications in international scientific journals subject to editorial control and with an H-index of 35","post_title":"Roberto Cusano","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"roberto-cusano","to_ping":"","pinged":"","post_modified":"2026-04-05 18:10:50","post_modified_gmt":"2026-04-05 16:10:50","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/roberto-cusano\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":10070,"post_author":"4","post_date":"2025-06-30 17:25:30","post_date_gmt":"2025-06-30 15:25:30","post_content":"Graduated in Computer Engineering at Universit\u00e0 \"La Sapienza\" of Rome, since 2014 he works as a technologist at CRS4. Here he deals with the design and implementation of distributed systems for the processing and storage of large volumes of scientific data (Big Data), with a particular focus on the use of micro-service architectures and the automation of their deployment.","post_title":"Marco Enrico Piras","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"marco-enrico-piras","to_ping":"","pinged":"","post_modified":"2026-04-05 18:13:16","post_modified_gmt":"2026-04-05 16:13:16","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/marco-enrico-piras\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":9959,"post_author":"4","post_date":"2025-06-30 17:26:39","post_date_gmt":"2025-06-30 15:26:39","post_content":"I'm a computer scientist and my areas of expertise are HPC, bigdataprocessing and machine learning, with scalability as a common thread.I have a background on parallel computing and foundational problemsmotivated by HPC, which I investigated during my PhD and during myyears as a PostDoc in Vienna.In the latest years I have worked, at the CRS4 research center, tobuild efficient and scalable bigdata and machine learning workflows. Ihave worked with streams of genomic and industrial data (using ApacheKafka and Flink as tools) and, within the DeepHealth European project,to the classification of gigapixel medical images, using bothTensorflow and the specialized EDDL ML library. In this context I havea built a scalable pipeline to efficiently manage datasets via the useof Apache Spark and Cassandra.","post_title":"Francesco Versaci","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"francesco-versaci","to_ping":"","pinged":"","post_modified":"2026-04-05 18:14:11","post_modified_gmt":"2026-04-05 16:14:11","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/francesco-versaci\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":10295,"post_author":"4","post_date":"2025-06-30 17:24:30","post_date_gmt":"2025-06-30 15:24:30","post_content":"Jessica Milia is a technologist in Biosciences and Computational Infrastructures, Smart Project and Quantum Computing sector of CRS4, NGS Core program. She graduated in Biology in 2018 at the University of Cagliari with a thesis focused on the identification and characterization of HIV-1 reverse transcriptase enxyme inhibitors. She got her master's degree in Cellular and Molecular Biology in 2020 at the University of Cagliari. Her thesis was focused on the evaluation of immune response inhibition mediated by Zika Virus. From December 2020 to October 2021 she worked as Research Fellow in the Laboratory of Molecular Virology of Department of Life and Environmental Sciences (University of Cagliari). Her main activities were: - evaluation of Sars-CoV-2 viral proteins inhibition of innate immune system and identification of potential inhibitors; - identification of Sars-CoV-2 nsp13 enzyme inhibitors. From December 2021 to current she works in the NGS sequencing platform of CRS4. She is involved in nucleic acids libraries preparation, performing and monitoring of sequencing experiments for WGS, WES, RNA-Seq, target sequencing, 16s Metagenomics experiments, using Illumina instruments. She helps to evaluate quality and quantity of sequencing raw data and bioinformatic analysis results.","post_title":"Jessica Milia","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"jessica-milia","to_ping":"","pinged":"","post_modified":"2026-04-05 18:12:25","post_modified_gmt":"2026-04-05 16:12:25","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/jessica-milia\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":93018,"post_author":"4","post_date":"2025-10-01 17:35:57","post_date_gmt":"2025-10-01 15:35:57","post_content":"Antonio Laus is a researcher in the Visual and Data-Intensive Computing (VIDIC) program at CRS4. After earning a Master's degree in Pharmacy from the University \"G. d'Annunzio\" of Chieti-Pescara and obtaining professional licensure, he began his research at the University of Cagliari, holding a fellowship focused on LC-QTOF-MS, metabolomics, and analytical method development for the characterization of biological samples. Since 2020, he has contributed as a Computer-Aided Drug Design (CADD) specialist to the EU project JUSTSO and to initiatives on New Psychoactive Substances (NPS), collaborating with international institutions including Ghent University and the NIDA (NIH). In 2023, he served as a research fellow in CADD at the Department of Life Sciences, University of Modena and Reggio Emilia, integrating molecular modeling and molecular dynamics with enhanced-sampling methods to study the thermodynamics and kinetics of biological systems and to design multitarget inhibitors (HDAC6 and Hsp90). In 2024, he became Principal Investigator of a project on the LEONARDO supercomputer (CINECA), in which he leads the development of AI-guided enhanced-sampling strategies to explore the conformational space of Hsp90 and optimize inhibitors for prostate cancer. His expertise includes docking, molecular modeling, molecular dynamics, alchemical methods, and enhanced sampling methods, as well as AI techniques for defining and optimizing collective variables. He has published as an author and co-author in peer-reviewed international journals and conference proceedings.","post_title":"Antonio Laus","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"antonio-laus","to_ping":"","pinged":"","post_modified":"2026-04-05 18:11:34","post_modified_gmt":"2026-04-05 16:11:34","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/antonio-laus\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":93000,"post_author":"4","post_date":"2025-10-01 17:35:38","post_date_gmt":"2025-10-01 15:35:38","post_content":"Elsi Ferro is a researcher in the Visual and Data-Intensive Computing (VIDIC) sector at CRS4. After graduating in Physics of Complex Systems at the Department of Physics of the University of Turin (2018), she worked as a researcher and later as a PhD student at the Department of Applied Science and Technology of the Politecnico di Torino and at the Italian Institute for Genomic Medicine (IIGM, Candiolo), collaborating also with international institutions including the University of Buenos Aires, where she spent part of her doctoral training. She then obtained her PhD in Physics (2024) and continued to work as a postdoctoral researcher at the Politecnico di Torino, before joining CRS4.Her main areas of expertise concern mathematical modeling and computational simulation of biological processes, in particular transcriptional genomics, post-transcriptional mechanisms, and regulation between proteins.","post_title":"Elsi Ferro","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"elsi-ferro","to_ping":"","pinged":"","post_modified":"2026-04-05 18:11:10","post_modified_gmt":"2026-04-05 16:11:10","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/people\/elsi-ferro\/","menu_order":0,"post_type":"people","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"\n |