{"id":10152,"date":"2025-06-30T17:22:09","date_gmt":"2025-06-30T15:22:09","guid":{"rendered":"https:\/\/www.crs4.it\/people\/gavin-brelstaff\/"},"modified":"2026-04-25T20:10:20","modified_gmt":"2026-04-25T18:10:20","slug":"gavin-brelstaff","status":"publish","type":"people","link":"https:\/\/www.crs4.it\/en\/people\/gavin-brelstaff\/","title":{"rendered":"Gavin Brelstaff"},"content":{"rendered":"","protected":false},"featured_media":4044,"template":"","meta":{"_acf_changed":false},"gruppo":[123],"class_list":["post-10152","people","type-people","status-publish","has-post-thumbnail","hentry","gruppo-data-intensive-computing-en"],"acf":{"name":"Gavin","surname":"Brelstaff","email":"gjb@crs4.it","phone":"","user_uuid":"e3bdea64-99fc-1032-95fe-0030485a3848","personal_page":"","google_scholar_id":"","position":"Researcher","project_coordinator":"","microsoft_academic_id":"","team_members":[{"ID":12561,"post_author":"4","post_date":"2025-07-03 18:17:44","post_date_gmt":"2025-07-03 16:17:44","post_content":"The LIFEMap Project \"From Pediatric Pathology to Cardiovascular and Neoplastic Diseases in Adults: Genomic Mapping for Personalized Medicine and Prevention\" - Trajectory 3 of the Operational Health Plan of the Ministry of Health - aims to identify pathological and sub-pathological conditions in children and\/or predictive genetic profiles associated with an increased risk of serious diseases in adults, taking into account environmental risk factors to develop personalized therapy and prevention plans for both children and adults.\n\u00a0For this purpose, the following will be undertaken:\n\n<li>Development of a federated database for the integration of genomic and phenotypic data;<\/li>\n<li>Utilization of a dataset (\u22655,000 patients) comprising clinical, genomic, and environmental (lifestyle) data for AI analysis;<\/li>\n<li>Recruitment of new cases, both pediatric and adult (5,000 patients), with detailed clinical characterization;<\/li>\n<li>Development of a scalable and reusable platform for the analysis and sharing of new data (1,400 WGS, 3,600 SNP);<\/li>\n<li>Identification of a series of genetic variants and profiles associated with the risk of developing obesity, chronic inflammatory diseases, pediatric neoplasms, and their complications in adulthood;<\/li>\n<li>Development of an AI analysis framework and application of Deep Learning for Network Medicine;<\/li>\n<li>Implementation of a biobank of samples, potentially reusable beyond the project's completion.<\/li>\n\nCRS4 will take part in the project with the following activities:\n<ul>\n<li>Whole Genome Sequencing on approximately 1,000 samples;<\/li>\n<li>development of scalable and reusable platforms for WGS data analysis for variant identification;<\/li>\n<li>genomic data modeling, standardization and sharing in international reference platforms;<\/li>\n<li>application of scalable platforms for WGS analysis and data sharing;<\/li>\n<li>scientific dissemination.<\/li>\n<\/ul>\n<ul>\n<\/ul>","post_title":"LIFEMAP","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"lifemap","to_ping":"","pinged":"","post_modified":"2026-04-16 10:00:05","post_modified_gmt":"2026-04-16 08:00:05","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/projects\/lifemap\/","menu_order":0,"post_type":"projects","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":12678,"post_author":"4","post_date":"2025-07-03 18:18:12","post_date_gmt":"2025-07-03 16:18:12","post_content":"The purpose of the ToPMa Project is the creation of tools and methodologies that enable the transfer of individual health data to personal repository systems made available to the citizens, in a continuous and automatic manner, from institutional and non-institutional sources, based on what is specified in an informed consent defined prior to the start of data transfer and dynamically modifiable at any time by the individuals.","post_title":"ToPMa","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"topma","to_ping":"","pinged":"","post_modified":"2026-04-02 12:32:14","post_modified_gmt":"2026-04-02 10:32:14","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/projects\/topma\/","menu_order":0,"post_type":"projects","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":19745,"post_author":"4","post_date":"2025-07-03 18:25:42","post_date_gmt":"2025-07-03 16:25:42","post_content":"Advances in networked audiovisual communication facilitate the emergence of computer-supported collaborative work (CSCW). In the COHERENT project, six leading European organisations provide complementary competencies to create a new networked holographic audio-visual platform to support real-time collaborative 3D interaction between geographically distributed teams. The display component will be based on innovative holographic techniques that can present, at natural human interaction scale, realistic animated 3D images to an unlimited number of freely moving simultaneous viewers. The design of the basic networked audiovisual components will be driven by two innovative demanding applications - a collaborative medical visualisation system and a collaborative design review system for the automotive industry - that will constitute by themselves an advancement of the state of the art in their specific domains. Both applications will provide intuitive access and interaction with shared 3D models through a sensory rich 3D user interface based on non-intrusive wireless interaction devices and offering 3D audio cues. Research will strongly concentrate on enabling technology for intuitive multi user access and interaction with complex 3D signals and objects. This project proposes to build a working high-resolution display in the one metre size range that, thanks to its human scale work area, will be ideally suited for multi-user collaborative working in true 3D. The challenge of providing the large visualisation data flow needed to drive such a device will be met using a cost-effective parallel solution based on commercial-off-the-shelf graphics and computing technology. Using GEANT, the pan-European Gigabit Research Network, the project will conduct distributed testing and validation of the system concepts for the two representative application scenarios. The research will be conducted in a 30-month schedule, to guarantee evaluation and demonstration of tangible results. Rapidly evolving advances in networked audiovisual communication technology are facilitating the emergence of computer-supported collaborative work (CSCW) systems. These systems are striving to seamlessly support collaboration between geographically distant teams for the purpose of achieving higher levels of participation, productivity, and creativity. They therefore address a major societal and economic challenge. Since visualisation is one of the most natural and intuitive ways to exchange information between humans, it has become the principal medium used in co-operative and multi-user situations. At the present time, however, state of the art collaborative real-time audiovisual systems typically rely on essentially 2D environments (traditional flat screens) to share information. For many professional applications, however, the main goal is to share the physical 3D object of common interest. These applications typically include clinical discussions among teams of medical specialists, multi-disciplinary scientific debate, design reviews between OEM's and suppliers using computer aided design (CAD), where the objects may be anatomical, molecular and product models respectively. Since these are almost exclusively very complex 3D objects, providing collaborative environments able to process, transmit and display 3D data in ways that match human perceptual abilities is therefore of primary importance and would represent a significant technology breakthrough. However, at present the only computer displays able to provide all the depth cues processed by the human brain to reconstruct a three-dimensional scene are unfortunately limited to single user configurations. Quite ironically, these limitations have led to networked solutions that facilitate remote collaboration only at the expense of the isolation of each participant from their local physical environment. In the COHERENT project, six leading European organisations in their respective fields provide complementary competencies to create a new networked holographic audio-visual platform striving to seamlessly support real-time collaborative 3D interaction between geographically distributed teams. The display component will be based on innovative holographic techniques that can present, at natural human interaction scale, realistic animated 3D images to an unlimited number of freely moving simultaneous viewers. The design of the basic networked audiovisual components will be driven by two innovative demanding applications - a collaborative medical visualisation system and a collaborative design review system for the automotive industry - that will constitute by themselves an advancement of the state of the art in their specific domains. Both applications will provide intuitive access and interaction with shared 3D models through a sensory rich 3D user interface based on non-intrusive wireless interaction and offering 3D audio cues. Research will strongly concentrate on enabling technology for intuitive multi user access and interaction with complex 3D signals and objects. The technical feasibility of the proposed holographic display solution has been recently demonstrated with the development of a ''small scale'' proof-of-concept, using white light based, 24 bit true colour, holographic 3D display. This project proposes to build on this earlier success to produce a working high-resolution display in the one metre size range that, thanks to its human scale work area, will be ideally suited for multi-user collaborative working in true 3D. The challenge of providing the large visualisation data flow needed to drive such a device will be met using a cost-effective parallel solution based on commercial-off-the-shelf graphics and computing technology. The driving applications have been chosen in two important sectors where collaborative 3D technology and networked audiovisual communication have a clear potential impact and provide a sizeable market for the future exploitation of the project results. Moreover, the need for distant teams to work together for a collaborative goal is becoming increasingly common in many industrial and social situations. Therefore, the best practice and methods opened-up by this project will have implications in other application domains. In particular, they will concern high potential, industry-driven domains such as next generation 3D-TV, electronic cinema, virtual and tele-presence and future mixed-reality-based communication services. The consortium has centred the project workplan around continuous and detailed end-user involvement in the research, development, evaluation, and validation activities. The end-users will also play an instrumental role in reaching their larger community as part of the dissemination and exploitation strategy. The research will be conducted against an ambitious, but achievable, 30-month schedule, to guarantee early delivery, evaluation, and demonstration of tangible results.","post_title":"COHERENT","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"coherent","to_ping":"","pinged":"","post_modified":"2026-04-02 12:38:46","post_modified_gmt":"2026-04-02 10:38:46","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/projects\/coherent\/","menu_order":0,"post_type":"projects","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":12572,"post_author":"4","post_date":"2025-07-03 18:17:49","post_date_gmt":"2025-07-03 16:17:49","post_content":"The continuing advances and increasing pervasiveness of simulation methods and data acquisition and processing tools enable us to measure and characterize natural and artificial objects, environments, and processes in ever greater detail and at ever higher generation rates. The fields of science, engineering, and technology are increasingly defined by data-driven approaches and need scalable solutions to make the most of the vast masses of information available. The study, development, and application of methods and technologies for processing, analyzing, exploring, and sharing massive and\/or complex data are, therefore, at the heart of all strategic research plans, both at the European and National scales and for regional smart specialization.\u00a0\nCRS4 actively contributes to this field of research and has now achieved a leading role in the national landscape. The institutional project XDATA, funded by the contribution under art. 9 L.R. 20\/2015, aims to consolidate and strengthen the center's activities in this strategic area and is divided into two parallel strands of activity:\n<ul>\n<li>The first stream, developed within the ViDiC sectore and leveraging synergies with initiatives at the national and international scale in the field of <strong>visual and data-intensive computing<\/strong>, focuses on scalable, and where possible shared and interoperable, enabling methods and technologies for acquiring, creating, processing, distributing and exploring complex and\/or massive datasets from simulations or measurements of real phenomena, objects, environments or processes. In particular, we will target our interest on: distributed computing, automation and machine learning solutions to improve the scalability of all processes; adaptive and intelligent visual computing methods for both the processing and understanding of geometric and visual data and their presentation; and management and sharing solutions based on data and process modeling using open formalisms, with a specific focus on the traceability and reproducibility of each process step. These general solutions will then be applied in vertical solutions in application areas that will include digital medicine, cultural heritage, and, more generally, digital science, engineering, and society.<\/li>\n<li>\nThe second strand, on the other hand, is developed within the Digital Technologies sectore, and focuses on the <strong>remote sensing<\/strong> supply chain, where the need emerges for a systematic structuring of processes for managing information flows, whether derived from satellite observation, aerial sensing, or ground-based networks, and the establishment of a persistent information base of aggregation of the time series of interest, functional for feeding models in the domains of interest and for multi-scenario representation of geographic output. The development of data fusion methodologies in the different spectral ranges, in line with the activities of ongoing projects, also requires the study of operational-type processing methodologies, especially where real-time requirements may be relevant. Application areas will mainly address the issues of resource access and environmental sustainability.\n<\/li>\n<\/ul>\n\u00a0\nIncluded in the project are specific activities targeting: research, development, and technology transfer; pilot studies; maintenance of dedicated research and development infrastructure; scientific dissemination; standardization activities; and other activities aimed at achieving greater integration with the scientific community and public and private entities.","post_title":"XDATA","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"xdata","to_ping":"","pinged":"","post_modified":"2026-04-02 12:32:06","post_modified_gmt":"2026-04-02 10:32:06","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.crs4.it\/projects\/xdata\/","menu_order":0,"post_type":"projects","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - 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