Sequencing and Genotyping Platform
Established in 2007 by the President of CRS4, Prof. Paolo Zanella, a former Head of the European Bioinformatics Institute near Cambridge in the UK, the Sequencing and Genotyping Platform offers a wide range of advanced genomic characterization techniques.
Offering its expertise in the field of gene expression and high processivity genotyping, researchers of the Platform provide partnership, scientific and technological know-how, advanced plant and equipment to aim the execution of high-tech projects. Research of the group is focused on the identification, isolation and characterization of genes and genetic pathways. They study diseases with a strong genetic component and high prevalence in the sardinian population like type I diabetes and multiple sclerosis, two autoimmune pathologies.
Researchers provide a quality support in the field of genetics and of molecular biology. The platform represents a technological resource not only for Technology Park researchers but even for external customers.
Thanks to its infrastructure, it provides experiment of:
microarray with different methodologies and approaches for expression or genomics studies
Sanger method to sequencing genomics DNA fragments
- massive DNA fragments “sequencing by synthesis” of oligonucleotides using reversible terminator-based sequencing chemistry .