CRS4 hosts the largest Next Generation Sequencing platform in Italy (1 x Illumina HiSeq3000, 1 x Illumina HiSeq2500, 2 x Illumina HiSeq2000 e 1 x Illumina MiSeq), with a throughput in 2016 of 10 TBase/month. The platform is directly interconnected to the CRS4 large scale computational resources.
This infrastructure, unique in Italy, enables CRS4 to perform large scale sequencing projects, from data production to analysis.
The NGS Core facility has been used for complex large-scale genetic analysis in a broad range of applications, including whole-genome and transcriptome sequencing, metagenomics, elucidation of DNA binding sites for chromatin and regulatory proteins, and human exome and targeted resequencing.
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